Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tubb3  tubulin, beta 3 class III   (Synonyms: 3200002H15Rik, betaIII-tubulin, Tuj1)
Results	Reference
1	J:223051 Albert M, Schmitz SU, Kooistra SM, Malatesta M, Morales Torres C, Rekling JC, Johansen JV, Abarrategui I, Helin K, The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3. PLoS Genet. 2013 Apr;9(4):e1003461
1*	J:63629 Baas D, Bumsted KM, Martinez JA, Vaccarino FM, Wikler KC, Barnstable CJ, The subcellular localization of OTX2 is cell-type specific and developmentally regulated in the mouse retina. Brain Res Mol Brain Res. 2000 May 31;78(1-2):26-37
1	J:201152 Bezzi M, Teo SX, Muller J, Mok WC, Sahu SK, Vardy LA, Bonday ZQ, Guccione E, Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery. Genes Dev. 2013 Sep 1;27(17):1903-16
1	J:335231 Bustamante-Barrientos FA, Mendez-Ruette M, Molina L, Koning T, Ehrenfeld P, Gonzalez CB, Wyneken U, Henzi R, Batiz LF, Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK. Front Cell Dev Biol. 2023;11:1061777
1	J:159309 Buttner N, Johnsen SA, Kugler S, Vogel T, Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7042-7
1	J:183920 Chen J, Lai F, Niswander L, The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15;26(8):803-15
1	J:305180 Choi I, Choi DJ, Yang H, Woo JH, Chang MY, Kim JY, Sun W, Park SM, Jou I, Lee SH, Joe EH, PINK1 expression increases during brain development and stem cell differentiation, and affects the development of GFAP-positive astrocytes. Mol Brain. 2016 Jan 8;9:5
1*	J:154619 Davis DA, Wilson MH, Giraud J, Xie Z, Tseng HC, England C, Herscovitz H, Tsai LH, Delalle I, Capzb2 interacts with beta-tubulin to regulate growth cone morphology and neurite outgrowth. PLoS Biol. 2009 Oct;7(10):e1000208
1	J:188897 Ghiani CA, Starcevic M, Rodriguez-Fernandez IA, Nazarian R, Cheli VT, Chan LN, Malvar JS, de Vellis J, Sabatti C, Dell'Angelica EC, The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth. Mol Psychiatry. 2010 Feb;15(2):115, 204-15
1*	J:138147 Gros-Louis F, Kriz J, Kabashi E, McDearmid J, Millecamps S, Urushitani M, Lin L, Dion P, Zhu Q, Drapeau P, Julien JP, Rouleau GA, Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish. Hum Mol Genet. 2008 Sep 1;17(17):2691-702
1	J:236559 Hasegawa K, Yasuda T, Shiraishi C, Fujiwara K, Przedborski S, Mochizuki H, Yoshikawa K, Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults. Nat Commun. 2016 Mar 14;7:10943
1	J:230934 Hashimoto M, Murata K, Ishida J, Kanou A, Kasuya Y, Fukamizu A, Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System. J Biol Chem. 2016 Jan 29;291(5):2237-45
1	J:157011 Hryciw T, MacDonald JI, Phillips R, Seah C, Pasternak S, Meakin SO, The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons. J Neurochem. 2010 Feb;112(4):924-39
1	J:253459 Inoue SI, Takahara S, Yoshikawa T, Niihori T, Yanai K, Matsubara Y, Aoki Y, Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice. Hum Mol Genet. 2017 Dec 1;26(23):4715-4727
1*	J:283020 Jeong B, Kim TH, Kim DS, Shin WH, Lee JR, Kim NS, Lee DY, Spastin Contributes to Neural Development through the Regulation of Microtubule Dynamics in the Primary Cilia of Neural Stem Cells. Neuroscience. 2019 Jul 15;411:76-85
1	J:341690 Ji F, Feng C, Qin J, Wang C, Zhang D, Su L, Wang W, Zhang M, Li H, Ma L, Lu W, Liu C, Teng Z, Hu B, Jian F, Xie J, Jiao J, Brain-specific Pd1 deficiency leads to cortical neurogenesis defects and depressive-like behaviors in mice. Cell Death Differ. 2023 Sep;30(9):2053-2065
1	J:306095 Ji F, Wang W, Feng C, Gao F, Jiao J, Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression. Mol Psychiatry. 2020 May 11;
1	J:165476 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T, Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci. 2010 Oct 20;30(42):13992-4007
1	J:146992 Kwon IS, Cho SK, Kim MJ, Tsai MJ, Mitsuda N, Suh-Kim H, Lee YD, Expression of Disabled 1 suppresses astroglial differentiation in neural stem cells. Mol Cell Neurosci. 2009 Jan;40(1):50-61
1	J:270401 Latremoliere A, Cheng L, DeLisle M, Wu C, Chew S, Hutchinson EB, Sheridan A, Alexandre C, Latremoliere F, Sheu SH, Golidy S, Omura T, Huebner EA, Fan Y, Whitman MC, Nguyen E, Hermawan C, Pierpaoli C, Tischfield MA, Woolf CJ, Engle EC, Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration. Cell Rep. 2018 Aug 14;24(7):1865-1879.e9
1	J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410
1	J:106707 Lien WH, Klezovitch O, Fernandez TE, Delrow J, Vasioukhin V, alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway. Science. 2006 Mar 17;311(5767):1609-12
1	J:280216 Liu W, Tang FL, Erion J, Xiao H, Ye J, Xiong WC, Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis. Mol Brain. 2014 Feb 11;7:10
1*	J:333071 Ma H, Su L, Xia W, Wang W, Tan G, Jiao J, MacroH2A1.2 deficiency leads to neural stem cell differentiation defects and autism-like behaviors. EMBO Rep. 2021 Jul 5;22(7):e52150
1	J:185466 MacDonald JI, Dietrich A, Gamble S, Hryciw T, Grant RI, Meakin SO, Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons. J Neurochem. 2012 Jun;121(6):861-80
1*	J:306206 Min JS, Halder D, Yoon JY, Jeon SJ, Jun SY, Lee JR, Lee JJ, Choi MH, Jung CR, Lee D, Kim BJ, Kim NS, Coiled-coil domain containing 50-V2 protein positively regulates neurite outgrowth. Sci Rep. 2020 Dec 4;10(1):21295
1	J:265044 Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-Gonzalez JL, Pico S, Hernandez IH, Diaz-Hernandez JI, Belloc E, Rodolosse A, Parikshak NN, Penagarikano O, Fernandez-Chacon R, Irimia M, Navarro P, Geschwind DH, Mendez R, Lucas JJ, Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature. 2018 Aug;560(7719):441-446
1	J:155110 Puig I, Champeval D, De Santa Barbara P, Jaubert F, Lyonnet S, Larue L, Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction. J Clin Invest. 2009 Dec;119(12):3586-96
1	J:174826 Rousselet E, Marcinkiewicz J, Kriz J, Zhou A, Hatten ME, Prat A, Seidah NG, PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. J Lipid Res. 2011 Jul;52(7):1383-91
1	J:173842 Tian Y, Lei L, Minden A, A key role for Pak4 in proliferation and differentiation of neural progenitor cells. Dev Biol. 2011 May 15;353(2):206-16
1	J:269323 Vazquez P, Hernandez-Sanchez C, Escalona-Garrido C, Pereira L, Contreras C, Lopez M, Balsinde J, de Pablo F, Valverde AM, Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation. J Lipid Res. 2018 Dec;59(12):2308-2320
1	J:337816 Wang W, Su L, Ji F, Zhang D, Wang Y, Zhao J, Jiao RD, Zhang M, Huang E, Jiang H, Zhang J, Jiao J, The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse. EMBO Rep. 2022 Feb 3;23(3):e53602
1	J:255060 Xia W, Jiao J, Histone variant H3.3 orchestrates neural stem cell differentiation in the developing brain. Cell Death Differ. 2017 Sep;24(9):1548-1563
1*	J:307957 Xie X, Wang S, Li M, Diao L, Pan X, Chen J, Zou W, Zhang X, Feng W, Bao L, alpha-TubK40me3 is required for neuronal polarization and migration by promoting microtubule formation. Nat Commun. 2021 Jul 5;12(1):4113
1	J:221409 Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF, Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 1;142(9):1616-27
1	J:108702 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM, Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20
1	J:326486 Zhang D, Liu C, Li H, Jiao J, Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors. Adv Sci (Weinh). 2020 Dec;7(23):2002117
1	J:329439 Zhang M, Su L, Wang W, Li C, Liang Q, Ji F, Jiao J, Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development. Cell Rep. 2022 Sep 13;40(11):111350
1	J:344223 Zhang W, Zhang R, Wu L, Zhu C, Zhang C, Xu C, Zhao S, Liu X, Guo T, Lu Y, Gao Z, Yu X, Li L, Chen ZJ, Qin Y, Jiao X, NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance. Cell Rep. 2023 Dec 26;42(12):113531
1	J:121660 Zhong J, Li X, McNamee C, Chen AP, Baccarini M, Snider WD, Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo. Nat Neurosci. 2007 May;10(5):598-607
1	J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639
1*	J:225508 Zou D, McSweeney C, Sebastian A, Reynolds DJ, Dong F, Zhou Y, Deng D, Wang Y, Liu L, Zhu J, Zou J, Shi Y, Albert I, Mao Y, A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors. Neural Dev. 2015;10:18
1	J:168571 Zou J, Zhou L, Du XX, Ji Y, Xu J, Tian J, Jiang W, Zou Y, Yu S, Gan L, Luo M, Yang Q, Cui Y, Yang W, Xia X, Chen M, Zhao X, Shen Y, Chen PY, Worley PF, Xiao B, Rheb1 is required for mTORC1 and myelination in postnatal brain development. Dev Cell. 2011 Jan 18;20(1):97-108